Touchstone Diabetes Center

Select Publications:

 

Shao M, Ishibashi J, Kusminski CM, Wang QA, Hepler C, Vishvanath L, MacPherson KA, Spurgin SB, Sun K, Holland WL, Seale P, and Gupta RK.  Zfp423 Maintains White Adipocyte Identity in Adult Mice. Cell Metabolism (Accepted)

Ye R, Wang QA, Tao C, Vishvanath L, Shao M, McDonald JG, Gupta RK, Scherer PE. Impact of tamoxifen on adipocyte lineage tracing: Inducer of adipogenesis and prolonged nuclear translocation of Cre recombinase. Mol Metab. 2015;4(11):771-8. Epub 2015/12/03. doi: 10.1016/j.molmet.2015.08.004. PubMed PMID: 26629402.


Wang QA, Tao C, Jiang L, Shao M, Ye R, Zhu Y, Gordillo R, Ali A, Lian Y, Holland WL, Gupta RK, Scherer PE. Distinct regulatory mechanisms governing embryonic versus adult adipocyte maturation. Nat Cell Biol. 2015;17(9):1099-111. Epub 2015/08/19. doi: 10.1038/ncb3217. PubMed PMID: 26280538; PMCID: PMC4553131.


Vishvanath L, MacPherson KA, Hepler C, Wang QA, Shao M, Spurgin SB, Wang MY, Kusminski CM, Morley TS, Gupta RK. Pdgfrbeta Mural Preadipocytes Contribute to Adipocyte Hyperplasia Induced by High-Fat-Diet Feeding and Prolonged Cold Exposure in Adult Mice. Cell Metab. 2015. Epub 2015/12/03. doi: 10.1016/j.cmet.2015.10.018. PubMed PMID: 26626462.


Neinast MD, Frank AP, Zechner JF, Li Q, Vishvanath L, Palmer BF, Aguirre V, Gupta RK, Clegg DJ. Activation of natriuretic peptides and the sympathetic nervous system following Roux-en-Y gastric bypass is associated with gonadal adipose tissues browning. Mol Metab. 2015;4(5):427-36. Epub 2015/05/15. doi: 10.1016/j.molmet.2015.02.006. PubMed PMID: 25973390; PMCID: PMC4421080.


Gupta OT, Gupta RK. Visceral Adipose Tissue Mesothelial Cells: Living on the Edge or Just Taking Up Space? Trends Endocrinol Metab. 2015;26(10):515-23. Epub 2015/09/29. doi: 10.1016/j.tem.2015.07.003. PubMed PMID: 26412153.


Ye R, Holland WL, Gordillo R, Wang M, Wang QA, Shao M, Morley TS, Gupta RK, Stahl A, Scherer PE. Adiponectin is essential for lipid homeostasis and survival under insulin deficiency and promotes beta-cell regeneration. Elife. 2014;3. Epub 2014/10/24. doi: 10.7554/eLife.03851. PubMed PMID: 25339419; PMCID: PMC4228265.


Wang QA, Scherer PE, Gupta RK. Improved methodologies for the study of adipose biology: insights gained and opportunities ahead. J Lipid Res. 2014;55(4):605-24. Epub 2014/02/18. doi: 10.1194/jlr.R046441. PubMed PMID: 24532650; PMCID: PMC3966696.


Kim M, Neinast MD, Frank AP, Sun K, Park J, Zehr JA, Vishvanath L, Morselli E, Amelotte M, Palmer BF, Gupta RK, Scherer PE, Clegg DJ. ERalpha upregulates Phd3 to ameliorate HIF-1 induced fibrosis and inflammation in adipose tissue. Mol Metab. 2014;3(6):642-51. Epub 2014/08/28. doi: 10.1016/j.molmet.2014.05.007. PubMed PMID: 25161887; PMCID: PMC4142394.


Gupta RK. Adipocytes. Curr Biol. 2014;24(20):R988-93. Epub 2014/12/03. doi: 10.1016/j.cub.2014.09.003. PubMed PMID: 25442852.


Asterholm IW, Rutkowski JM, Fujikawa T, Cho YR, Fukuda M, Tao C, Wang ZV, Gupta RK, Elmquist JK, Scherer PE. Elevated resistin levels induce central leptin resistance and increased atherosclerotic progression in mice. Diabetologia. 2014;57(6):1209-18. Epub 2014/03/14. doi: 10.1007/s00125-014-3210-3. PubMed PMID: 24623101; PMCID: PMC4106234.


Wang QA, Tao C, Gupta RK, Scherer PE. Tracking adipogenesis during white adipose tissue development, expansion and regeneration. Nat Med. 2013;19(10):1338-44. Epub 2013/09/03. doi: 10.1038/nm.3324. PubMed PMID: 23995282; PMCID: PMC4075943.


Gupta RK, Mepani RJ, Kleiner S, Lo JC, Khandekar MJ, Cohen P, Frontini A, Bhowmick DC, Ye L, Cinti S, Spiegelman BM. Zfp423 expression identifies committed preadipocytes and localizes to adipose endothelial and perivascular cells. Cell Metab. 2012;15(2):230-9. Epub 2012/02/14. doi: 10.1016/j.cmet.2012.01.010. PubMed PMID: 22326224; PMCID: PMC3366493.


Gupta RK, Rosen ED, Spiegelman BM. Identifying novel transcriptional components controlling energy metabolism. Cell Metab. 2011;14(6):739-45. Epub 2011/12/14. doi: 10.1016/j.cmet.2011.11.007. PubMed PMID: 22152302; PMCID: PMC3240865.


Gupta RK, Arany Z, Seale P, Mepani RJ, Ye L, Conroe HM, Roby YA, Kulaga H, Reed RR, Spiegelman BM. Transcriptional control of preadipocyte determination by Zfp423. Nature. 2010;464(7288):619-23. Epub 2010/03/05. doi: 10.1038/nature08816. PubMed PMID: 20200519; PMCID: PMC2845731.

 

Complete List of Published Work by R. Gupta:

 

 

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